Genetics & Discussion Of ALS, With Stuart Millheiser

By Jason McDonald


If you want to talk about ALS, in terms of remedies and the like, you will find that there isn't much to talk about. Information in this regard is scarce, meaning that research is rendered that much more vital. Stuart Millheiser can tell you the same, but it seems like there may be a genetic component associated with the aforementioned condition. If you're inquisitive about what this exactly means, perhaps a study that was published recently is of interest to you.

As an article on Genetic Literacy Project detailed, around 90 percent of ALS cases are unknown, as far as their origins are concerned. With that said, there has been speculation that the other 10 percent or so may have some sort of connection genetics. To push this idea along, a study in the American Journal of Human Genetics covered C9orf72, which is a type of gene that may have some kind of influence on ALS. Mutations were observed in five offspring. What's interesting is that while four out of those five cases were diagnosed with this condition, their parents and grandparents were not.

I am sure that Stuart Millheiser and others can attest to the intrigue associated with the study. The article also mentioned that C9orf72 is routinely observed in healthy neurons, within the nuclear membrane to be more precise. However, when it comes to diseased neurons, the aforementioned gene is seen in the plasma membrane. This plays negatively into the idea of protein, which is needed in order to keep muscular functions at a high level.

These details go to show that ALS has numerous variables, most of which we don't have solid information about. Of course, this isn't to say that assistance is unavailable; as a matter of fact, we are able to influence matters for the better. The likes of Stuart Millheiser can attest to the fact that the general public can offer donations or monthly payments, both of which can be used to fund research. Without it, studies such as this stand a lesser chance of being carried out.

I am sure that anyone can agree with the notion that information is nothing short of useful. Details like these are worthwhile, not only for those who are involved in science but those who consider themselves activists as well. For those who are part of the general public but would still like to help, it's easy to see that donations and the like can be offered. Considering the impact that ALS can have, any amount that's given can have a big impact.




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